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GT Voice: China-S.Korea 'cool' trade flourishes amid heat waves_我的网站

别有用心的单身女

一 |

A view of the Seoul skyline Photo: VCG
South Korea is grappling with scorching heat waves this summer, with temperatures soaring above 40 C in its capital city of Seoul for the first time since 2018. The extreme weather has dominated newspaper headlines lately, which has wreaked havoc on the people's health and agricultural production there.
For instance, with mass die-offs at the country's fish farms and catches declining, seafood prices are trending higher, according to South Korean media reports. Meanwhile, South Korean consumers' demand for cooling products is surging.
Against this backdrop, the unique strengths of China-South Korea economic and trade cooperation - characterized by flexible responses and regional short-chain supply arrangements - have been fully demonstrated.
Unlike countries in Europe and elsewhere in the West, or regions that rely on long-distance transportation, China and South Korea share geographical proximity and mature cross-border logistics system. Built through years of in-depth industrial collaboration, their circulation network drastically shortens supply chain routes and turnover cycles, delivering vital response in time of need.
Since the onset of the summer heat waves, a diverse array of Chinese-made goods - frozen beverages, portable handheld fans, pet cooling accessories and others - has flowed to the South Korean market. The rapid replenishment has provided relief to South Koreans grappling with soaring temperatures.
The "cool" trade that has blossomed between the two countries is fundamentally a story of mutual benefit and complementary strengths. While Chinese cooling supplies enter the South Korean market, Chinese consumers' demand for South Korean summer cosmetics and personal care products is heating up too. These two seemingly separate trade flows essentially reflect the deep-seated trade complementarity between the two neighbors.
Since the beginning of summer, "cool-feeling" cosmetics have become a shopping hit among Chinese consumers. Many South Korean products, featuring lightweight textures, durability and sweat-proof performance, have won growing market popularity.
The two-way trade flow is rooted in the alignment of the two countries' industrial structures and consumer needs, allowing both consumers to access what they require in the trade of "cool products" and achieve mutually beneficial outcomes.
The structural underpinnings of this synergy run deep. China's strength in agricultural production, cold‑chain infrastructure, and large‑scale manufacturing complements South Korea's prowess in beauty product research and development, good quality control and sophisticated brand operation. Most importantly, their geographical proximity allows such industrial complementarity to flourish.
From a broader perspective, global climate change seems to continue interfering with economic life in increasingly unpredictable ways. Caught in this dual pressure of escalating climate shock and global industrial restructuring, the significance of regional economic cooperation is being redefined. It is no longer limited to expanding market access and cutting operational costs; instead, it is deeply tied to safeguarding people's basic livelihoods in time of sudden unexpected disruptions.
The shortened transportation window brought by geographical proximity boosts the supply chain's response speed, enabling it to swiftly counter market volatility triggered by sudden emergencies.
The deep industrial integration that China and South Korea have nurtured over the past decades across sectors including electronics, beauty, agricultural products and cold-chain logistics has laid an exceptionally solid foundation for bilateral cooperation.
Currently, global supply chains are facing shocks from geopolitical conflicts, rising trade barriers as well as surging extreme weather patterns, leaving many long-distance global supply chains increasingly fragile and prone to sudden breakdowns.
The short-chain cooperation between China and South Korea has demonstrated that, in the era of growing uncertainties in the world, tapping deeper into regional industrial complementary advantages and building more stable and flexible cross-border industrial and supply chains is both an efficient choice to reduce circulation costs and a practical path to fend off risks to ensure industrial stability and protect people's livelihood.
。由麦凯尔维工程学院机械工程和材料科学的Lilyan & E. Lisle Hughes教授Srikanth Singamaneni和Singamaneni实验室的前博士后Anushree Seth领导的研究人员开发了FluoroDOT测定法。该研究最近发表在《细胞报告方法》上。这种高度敏感的检测方法能够在大约30分钟内看到并测量单个细胞分泌的蛋白质。

二 | 树突状细胞在不同时间点分泌蛋白1（TNFa，红色显示）和蛋白2（IL-6，黄色显示）的FluoroDOT检测图像（从左到右。未受刺激、受刺激30分钟、1小时、2小时和3小时）。细胞的细胞核以蓝色显示。白色箭头突出显示了只分泌一种蛋白质或两种蛋白质的不同数量和不同时间点的细胞。图像: Srikanth Singamaneni/华盛顿大学与来自其他大学和华盛顿大学医学院的科学家一起发现FluoroDOT检测法用途广泛，价格低廉，可适应任何实验室环境，并且有可能比目前常用的检测法更全面地了解这些蛋白质。生物医学研究人员通过分泌蛋白来了解细胞间通讯、细胞信号传导、激活和炎症等方面的信息，但目前的方法在敏感性方面受到限制，而且可能需要24小时的繁琐处理流程。质子-荧光是Singamaneni实验室创造的一种质子增强的纳米标签，比传统的荧光标签亮16000倍，信噪比超过30倍，这是FluoroDOT检测法与其他检测法的区别所在。Singamaneni说："质子-荧光剂是由金属纳米粒子组成的，它作为天线拉入光线并增强分子荧光团的荧光发射，从而使它成为一种超亮的纳米粒子。

三 | "这种质子-荧光的超亮发射使用户能够看到极少量的分泌蛋白，这是他们在现有测定法中无法做到的，加上利用定制的算法，用每个簇或斑点的颗粒数量或点状图案，实现以数字方式测量高分辨率信号。此外，它不需要特殊设备。Singamaneni和他的合作者于2020年在《自然-生物医学工程》杂志上首次发表了他们的等离子体氟化物工作。

四 | 这项正在申请专利的质子荧光技术由圣路易斯华盛顿大学技术管理办公室授权给Auragent生物科学有限公司。"使用一个简单的荧光显微镜，我们能够同时对一个细胞以及它周围分泌的蛋白质的空间分布进行成像，"Seth说，他作为Singamaneni实验室的博士后学者从事这个项目，并作为Auragent生物科学公司的首席科学家（细胞应用）继续从事这项工作。"我们看到不同细胞类型的有趣分泌模式。

五 | 这种检测方法还能同时观察来自单个细胞的两种类型的蛋白质。当多个细胞受到相同的刺激时，我们可以将同时分泌两种蛋白质的细胞与只分泌一种蛋白质或根本不分泌的细胞区分开来。"为了验证这项技术，该团队使用了从人类和小鼠细胞中分泌的蛋白质，包括感染了结核分枝杆菌的免疫细胞。合作者和共同作者之一，医学博士Jennifer A. Philips，医学和分子微生物学系的Theodore和Bertha Bryan教授，以及医学院传染病科的共同主任，已经在她的实验室中使用了FluoroDOT测定。